Total and Fetal Circulating Cell-Free DNA, Angiogenic, and Antiangiogenic Factors in Preeclampsia and HELLP Syndrome
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چکیده
منابع مشابه
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15 صفحه اولCirculating angiogenic factors in the pathogenesis and prediction of preeclampsia.
Preeclampsia is a major cause of maternal, fetal, and neonatal mortality worldwide. Although the etiology of preeclampsia is still unclear, recent studies suggest that its major phenotypes, high blood pressure and proteinuria, are due in part to excess circulating soluble fms-like tyrosine kinase-1 concentrations. Soluble fms-like tyrosine kinase-1 is an endogenous antiangiogenic protein that i...
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The placenta plays a central role in governing local circulatory system that mediates maternal condition and fetal growth. In early gestational phases, the placenta exerts properties of invasion and neovascularization for successful placentation. Extravillous invasive trophoblasts replace uterine endometrial vasculature and establish local blood pathway to obtain oxygen and nutrients from the m...
متن کاملEarly preeclampsia and HELLP syndrome in a 20 week pregnant patient
The first time Weinstein in 1982 described patients with the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP) in pregnant preeclamptic and eclamptic patients. This syndrome is a severe form of preeclampsia or eclampsia. Usually HELLP syndrome occurs at the third trimester and only 15% occur before the 27th week of pregnancy and rarely before the 20th week of pregna...
متن کاملAngiogenic Factors in Preeclampsia
Preeclampsia is one of the most frequently encountered hypertensive complication of pregnancy that affect ≈5% of pregnant women worldwide. It is often characterized by new onset of hypertension and proteinuria, usually during the last trimester of pregnancy, and is commonly associated with edema and hyperuricemia. Preeclampsia occurs only in the presence of the placenta, even when there is no f...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2017
ISSN: 0895-7061,1941-7225
DOI: 10.1093/ajh/hpx024